EXCELSE™ formulation technology
It’s a matter of concentration
Some proteins are effective only at high doses requiring larger volumes or concentrated delivery, which creates inconvenience for patients and higher costs for payers.
The groundbreaking EXCELSE™ high-concentration formulation technology uses customized blends of amino acids to highly stabilize and concentrate delicate biotechnology medicines. This is achieved by using a proprietary blend of amino acids that coats key regions of the molecule, allowing them to be concentrated together without clumping or becoming unstable.
For each target molecule, the blend is optimized for concentration, aggregation, syringeability, and stability. Upon injection, the amino acids disperse allowing the undamaged drug to quickly enter the blood stream.
- Permits concentration of intravenous liquid and lyophilized biologics into liquid subcutaneous injections
- Significant viscosity reduction
- Concentrations of up to 250 mg/ml allowing 1 ml injections
- No change to molecule is required
- Proprietary optimized blends of amino acid stabilizers allow high protein concentration and protein stablization
- Stabilizers are non-active and FDA approved